NIH Library of Medicine PubMed Central

Journal List  Medicine (Baltimore)  v.95(40); 2016 Oct  PMC5059044

Background: In China, acupuncture has been proposed as a potential treatment for chronic obstructive pulmonary disease (COPD). However, the current evidence lacks sufficient support to firmly establish the effectiveness of acupuncture in COPD. Therefore, this multicenter, randomized, sham-controlled study was devised to assess the efficacy of acupuncture in treating patients with COPD.

Methods: This is a two-arm, parallel-group, multicenter, randomized, sham-controlled trial with concealed allocation, ensuring blinding of participants, assessors, and analysts. Seventy-two COPD participants were recruited and randomly assigned to two groups (real acupuncture group and sham acupuncture group) in a 1:1 ratio. Patients underwent either real or sham needling at identical acupoints three times weekly for 8 weeks. The primary outcome measured was dyspnea on exertion, evaluated using the 6-minute walk test. Additionally, health-related quality of life was assessed. Measurements were taken at baseline and after 8 weeks of treatment.

Results: Significant improvements in the six-minute walking distance and health-related quality of life were observed in the real acupuncture group compared to the sham acupuncture group.

Conclusion: The findings suggest that acupuncture can serve as an adjunctive therapy to alleviate dyspnea in patients with COPD.

背景: 在中國,針灸被提議作為治療慢性阻塞性肺病(COPD)的一種可能方法。然而,目前的證據不足以得出針對COPD中針灸療效的明確結論。因此,設計了這項多中心、隨機、假控制研究,旨在評估針灸治療COPD患者的效果。

方法: 這是一項雙臂、平行組、多中心、隨機、假控制的試驗,有隱藏的分配,確保了參與者、評估者和分析者的盲法。共招募了72名COPD患者,並按1:1比例隨機分為2組(真針灸組和假針灸組)。患者每週接受相同穴位的真針灸或假針灸3次,為期8週。主要結果是使用6分鐘步行測試評估的運動性呼吸困難。此外,還評估了健康相關生活質量。測量在基線和治療後8週進行。

結果: 真針灸組的六分鐘步行距離和健康相關生活質量明顯優於假針灸組。

結論: 研究結果表明,針灸可作為輔助療法,減輕COPD患者的運動性呼吸困難。

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